Studies on the plasma tryptophan and urinary 5-hydroxy-3-indoleacetic acid in expedition members residing in Antarctica

Shuhuai, Xu and Quanfu, Xue and Zuohong, Xue and Zonghui, Wang (1997) Studies on the plasma tryptophan and urinary 5-hydroxy-3-indoleacetic acid in expedition members residing in Antarctica. Advances in Polar Science, 8 (1). pp. 72-76.

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Abstract

In order to clarify the possible relationship between the changes of behavior/personality and metabolic changes of 5-hydroxytryptamine (5-HT) in Antarctic expedition members, plasma tryptophan (Trp) and urinary 5-hydroxy-3-indoleacetic acid (5-HIAA) were studied for 24 winter-over and 19 summer-over members of the 8th and 11th CHINARE respectively. Results showed that plasma Trp decreased significantly after residing 1-3 months at Great Wall Station and did not recover on returning back to Beijing from Antarctica by two weeks travelling. Urinary 5-HIAA increased significantly after residing 6 months at Great Wall Station, and recovered on returning back to Beijing from Antarctica in the winter-over members. The decrease of plasma Trp may be related to the decline of brain 5-HT which might play a role in the changes of behavior/personality. Increase of urinary 5-HIAA might reflect metabolic changes of 5-HT as a whole, but cold weather involving in the release response of platelet should be considered. Therefore, supplement of related food rich in Trp or intervention of L-Trp might be valuable.

Item Type:	Article
Related URLs:
Keywords:	Antarctica, expedition member, tryptophan, 5-hydroxy-3-indoleacetic acid.
Subjects:	Unspecified
Organizations:	Unspecified
Date Deposited:	21 Apr 2023 11:17
URI:	http://library.arcticportal.org/id/eprint/2129

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